What is CBD?
There are over 400 components found within the Cannabis plant, of which 66 have been classified as cannabinoids. Cannabidiol, also known as CBD, is one of those compounds found in the cannabis plant.
CBD has many medical benefits and is the ideal choice for patients who are seeking a proven alternative treatment. CBD is commonly used as an antiemetic, anticonvulsant, antipsychotic, anti-inflammatory, anti-oxidant, antitumor/anti-cancer and anti-depressant.
There are currently several methods used to extract CBD. There are four known methods for extraction:
- Hydrocarbons such as benzene, hexane, and butane.
- Supercritical fluid extraction such as CO2.
- Uncompressed liquid solvents such as ethanol, methanol, petroleum or naphtha.
- Food grade solvents such as olive oil.
The first extraction method uses compressed liquid hydrocarbons. The hydrocarbons commonly used are Benzene, Hexane, Butane, and Propane. These hydrocarbons are all highly flammable and the risk of an explosion happening during the evaporation phase is extremely high. In addition, there are high levels of residue in the extract that can be toxic and dangerous if consumed.
The second extraction method is a process called Supercritical Fluid Extraction or commonly known as SFE. Carbon dioxide (CO2) is the most used supercritical fluid for extraction because considered the most non-hazardous of all methods. The downfall for this method is that the process is slow and complex and ability to keep the carbon dioxide at the right high-pressure level is quite expensive.
The third method uses uncompressed liquid solvents, this system is commonly referred as the Rick Simpson Method, which uses petroleum or naphtha as a solvent. Other possible solvents used for this method can be ethanol or methanol.
The final method uses food grade solvents in order to extract the cannabinoids. The benefits of this method lies in its simplicity. The downfall is that the extract cannot be concentrated.
The major drawback of all these extraction methods is that the process extracts other unwanted compounds.
See graph to the right taken from a university study in Italy-
How Cavitation can help?
Cavitation Technology is introducing another method. Cavitation Technologies, Inc. developed high-efficiency technologies covered by 24 plus patents for processing fluids in various industries and is uniquely positioned to provide their technology to pharmaceutical and medical cannabis industry. CTI has engineered a system for extraction that utilizes cutting-edge cavitation technology that is able to achieve higher yield comparing to existing methods. The new system for extraction, in addition to the minor modification to their existing extraction machines, allows suppliers the ability to improve the quality of their extractions.
The unique physical process and cavitation wave can break or deform plant cell tissues and enhance the strength of solute particle vibration, acceleration shock, and sound pressure. Local extreme high temperature and pressure formed on materials make large-volume herbal medicines fully exposed to the cavitation, which accelerates uniform precipitation of active ingredients and significantly increases extraction rate compared with traditional techniques. Cavitation extraction works under normal temperature and effectively reduces the loss of heat-sensitive components. The advantages of CTI’s extraction methods is that allows for a high extraction rate in a short amount of time, nontoxic or hazardous chemicals are used, low cost, green extraction and its environmentally friendly.
Why is hydrodynamic cavitation better for CBD?
Cavitation creates nanoemulsions which helps improve the delivery of active pharmaceutical ingredients. Nanoemulsions are developed to be an advanced method for drug delivery systems to help overcome any disadvantages associated with traditional drug delivery systems. Nanoemulsions are far superior to macroemulsions, due to their versatility and unique properties. This allows for thermodynamic stability, an increase in drug solubilization, bioavailability, rapid dissolution after administration, a higher concentration of bioactive cannabinoids, bacteria free and is safer for long time use.